Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
Abstract
A plant of the Apocynaceae family, Gymnema sylvestre, is included and used as a traditional therapy for various purposes. It is being used as a dietary supplement because it has numerous therapeutic benefits. In this paper, reviews mainly focused on Gymnema sylvestre and its bioactive components effect on human cancer cell (in vitro) and oxidative stress. In order to write this review which provides a comprehensive review of Gymnema sylvestre showing promising anticancer and antioxidant activity relevant information was collected from scientific journals, and research papers. Due to the presence of bioactive compounds in Gymnema sylvestre such as flavonol glycoside, lupeol, sterols, triterpenoid saponins, dammarene saponins and triterpene saponins, it can act as a promising cytotoxic and anticancer agent against several human cancer cell lines. Therefore, G. sylvestre has been shown to be effective against cancer development and progression and oxidative stress, and should be considered safe and effective to use in cancer prevention and therapy and as an antioxidant.
Karami, M., & Movahedi, A. (2022). A Review of In Vitro and In Vivo Anti-oxidant and Anti-Cancer Activities of Gymnema Sylvestre. Biomacromolecular Journal, 8(1), 35-46.
MLA
Mahya Karami; Ariyo Movahedi. "A Review of In Vitro and In Vivo Anti-oxidant and Anti-Cancer Activities of Gymnema Sylvestre". Biomacromolecular Journal, 8, 1, 2022, 35-46.
HARVARD
Karami, M., Movahedi, A. (2022). 'A Review of In Vitro and In Vivo Anti-oxidant and Anti-Cancer Activities of Gymnema Sylvestre', Biomacromolecular Journal, 8(1), pp. 35-46.
VANCOUVER
Karami, M., Movahedi, A. A Review of In Vitro and In Vivo Anti-oxidant and Anti-Cancer Activities of Gymnema Sylvestre. Biomacromolecular Journal, 2022; 8(1): 35-46.
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